Linavonkibart
Linavonkibart (SRK 181) is a high-affinity, fully human antibody that selectively binds to latent TGFβ1 and inhibits its activation. Linavonkibart plays an important role in cancer[1].
Product Specifications
CAS Number
[2640981-30-0]
Product Name Alternative
SRK-181
UNSPSC
12352203
Target
Others
Type
Inhibitory Antibodies
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/linavonkibart.html
Purity
95.69
Solubility
10 mM in DMSO
Smiles
[Linavonkibart]
Molecular Weight
(144.7 kDa)
References & Citations
[1]Brian T Welsh, et al. Nonclinical Development of SRK-181: An Anti-Latent TGFβ1 Monoclonal Antibody for the Treatment of Locally Advanced or Metastatic Solid Tumors. Int J Toxicol. 2021 May-Jun;40 (3) :226-241.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 1
Available Sizes
Curated Selection
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