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Linavonkibart

Linavonkibart (SRK 181) is a high-affinity, fully human antibody that selectively binds to latent TGFβ1 and inhibits its activation. Linavonkibart plays an important role in cancer[1].

Product Specifications

CAS Number

2640981-30-0

Product Name Alternative

SRK-181

UNSPSC

12352203

Target

Others

Type

Inhibitory Antibodies

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/linavonkibart.html

Purity

95.69

Solubility

10 mM in DMSO

Smiles

[Linavonkibart]

Molecular Weight

(144.7 kDa)

References & Citations

[1]Brian T Welsh, et al. Nonclinical Development of SRK-181: An Anti-Latent TGFβ1 Monoclonal Antibody for the Treatment of Locally Advanced or Metastatic Solid Tumors. Int J Toxicol. 2021 May-Jun;40 (3) :226-241.

Shipping Conditions

Dry Ice

Storage Conditions

-80°C

Scientific Category

Inhibitory Antibodies

Clinical Information

Phase 1

Available Sizes

Frequently Asked Questions

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