E3 ligase Ligand 13
Product Specifications
UNSPSC Description
E3 ligase Ligand 13 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 13 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
Target Antigen
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-13.html
Solubility
10 mM in DMSO
Smiles
OC([C@H](NC([C@H](O)[C@@H](NC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)CC4=CC=CC=C4)=O)CC(C)C)=O
Molecular Weight
530.61
References & Citations
[1]Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-128810/E3-ligase-Ligand-13-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-128810/
Clinical Information
No Development Reported
CAS Number
2701565-75-3
Available Sizes
Curated Selection
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