Nicastrin, Mouse (HEK293, hFc)
Nicastrin is an important subunit of the γ-secretase complex and plays a key role in the endoproteolytic cleavage of integral membrane proteins, including Notch receptors and amyloid-β precursor protein (APP) . In the γ-secretase complex, nicastin acts as a key regulator of Notch and Wnt signaling cascades and affects downstream processes. Nicastrin Protein, Mouse (HEK293, hFc) is the recombinant mouse-derived Nicastrin protein, expressed by HEK293 , with C-hFc labeled tag.
Product Specifications
Product Name Alternative
Nicastrin Protein, Mouse (HEK293, hFc), Mouse, HEK293
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/nicastrin-protein-mouse-hek293-hfc.html
Molecular Formula
59287 (Gene_ID) P57716 (G28-E668) (Accession)
Molecular Weight
Approximately 117 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Shipping Conditions
Dry ice.
Scientific Category
Recombinant Proteins
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