Famotidine-d4
Famotidine-d4 (MK-208-d4) is deuterium labeled Famotidine. Famotidine (MK-208) is a competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion[1].
Product Specifications
CAS Number
2707433-64-3
Product Name Alternative
MK-208-d4
UNSPSC
12352005
Target
Histamine Receptor; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others
Field of Research
Metabolic Disease; Endocrinology; Cancer; Cardiovascular Disease
Smiles
NS(/N=C(C([2H])(C([2H])(SCC1=CSC(/N=C(N)\N)=N1)[2H])[2H])\N)(=O)=O
Molecular Formula
C8H11D4N7O2S3
Molecular Weight
341.47
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Inan, A., et al., Effects of the histamine H2 receptor antagonist famotidine on the healing of colonic anastomosis in rats. Clinics (Sao Paulo), 2009. 64 (6) : p. 567-70.|[3]Miyata, K., et al., Studies on the mechanism for the gastric mucosal protection by famotidine in rats. Jpn J Pharmacol, 1991. 55 (2) : p. 211-22.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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