Quinoclamine
Quinoclamine, a naphthoquinone derivative, is a NF-κB inhibitor. Quinoclamine exhibits anti-cancer activity[1][2].
Product Specifications
CAS Number
2797-51-5
UNSPSC
12352005
Hazard Statement
H302, H319, H331, H400
Target
NF-κB
Type
Reference compound
Related Pathways
NF-κB
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/quinoclamine.html
Concentration
10mM
Purity
99.55
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(C(Cl)=C(C1=O)N)C2=C1C=CC=C2
Molecular Formula
C10H6ClNO2
Molecular Weight
207.62
Precautions
H302, H319, H331, H400
References & Citations
[1]Kwon H , et al. Induction of differentiation of U-937 cells by 2-chloro-3-amino-1,4-naphthoquinone. Res Commun Mol Pathol Pharmacol. 1997 Aug;97 (2) :215-27.|[2]Cheng WY, et al. Comprehensive evaluation of a novel nuclear factor-kappaB inhibitor, quinoclamine, by transcriptomic analysis. Br J Pharmacol. 2009 Jul;157 (5) :746-56.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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