Quinoclamine

Quinoclamine, a naphthoquinone derivative, is a NF-κB inhibitor. Quinoclamine exhibits anti-cancer activity[1][2].

Product Specifications

CAS Number

[2797-51-5]

UNSPSC

12352005

Hazard Statement

H302, H319, H331, H400

Target

NF-κB

Type

Reference compound

Related Pathways

NF-κB

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/quinoclamine.html

Concentration

10mM

Purity

99.55

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(C(Cl)=C(C1=O)N)C2=C1C=CC=C2

Molecular Formula

C10H6ClNO2

Molecular Weight

207.62

Precautions

H302, H319, H331, H400

References & Citations

[1]Kwon H , et al. Induction of differentiation of U-937 cells by 2-chloro-3-amino-1,4-naphthoquinone. Res Commun Mol Pathol Pharmacol. 1997 Aug;97 (2) :215-27.|[2]Cheng WY, et al. Comprehensive evaluation of a novel nuclear factor-kappaB inhibitor, quinoclamine, by transcriptomic analysis. Br J Pharmacol. 2009 Jul;157 (5) :746-56.