Piperidine-GNE-049-N-Boc
Piperidine-GNE-049-N-Boc is a ligand for target protein for PROTAC of dCBP-1. dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP[1].
Product Specifications
CAS Number
1936431-36-5
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/piperidine-gne-049-n-boc.html
Purity
98.48
Solubility
1M HCl : 32.5 mg/mL (ultrasonic; adjust pH to 1 with HCl)
Smiles
O=C(N1CCC(N(C2CCNCC2)N=C3N4CCCC5=C4C=C(C(F)F)C(C6=CN(C)N=C6)=C5)=C3C1)OC(C)(C)C
Molecular Formula
C30H39F2N7O2
Molecular Weight
567.67
References & Citations
[1]Vannam R, et, al. Targeted degradation of the enhancer lysine acetyltransferases CBP and p300. Cell Chem Biol. 2020 Dec 31; S2451-9456 (20) 30513-4.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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