MPT0B002
MPT0B002 is a potent microtubule inhibitor with anticancer activities. MPT0B002 disrupts tubulin polymerization, induces apoptosis, and arrests cell cycle at the G2/M phase[1].
Product Specifications
CAS Number
946077-08-3
UNSPSC
12352005
Target
Apoptosis; Microtubule/Tubulin
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mpt0b002.html
Smiles
O=C(C1=CC(OC)=C(C(OC)=C1)OC)C2=CC3=C(C=C2)N(C=C3)C
Molecular Formula
C19H19NO4
Molecular Weight
325.36
References & Citations
[1]Yi-Yen Yeh, et al. MPT0B002, a novel microtubule inhibitor, downregulates T315I mutant Bcr-Abl and induces apoptosis of imatinib-resistant chronic myeloid leukemia cells. Invest New Drugs. 2017 Aug;35 (4) :427-435.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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