Disodium 5'-inosinate

Disodium 5'-inosinate (IMP disodium salt) is a nucleotide-based umami agent. Disodium 5'-inosinate can bind to umami receptors and stimulate taste nerves, allowing the brain to perceive umami. In addition, Disodium 5'-inosinate produces a transient behavioral excitement in mice[1][2].

Product Specifications

CAS Number

[4691-65-0]

Product Name Alternative

IMP (disodium salt) ; Disodium inosinate

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/disodium-5-inosinate.html

Purity

99.74

Solubility

DMSO : < 1 mg/mL|H2O : 250 mg/mL (ultrasonic)

Smiles

O=P(OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C(N=CN=C32)O)O1)O)O)(O[Na])O[Na]

Molecular Formula

C10H11N4Na2O8P

Molecular Weight

392.17

Precautions

H302, H315, H319, H335

References & Citations

[1]Adachi A, et al. Neuronal responses of the nucleus tractus solitarius to oral stimulation with umami substances. Physiol Behav. 1991 May;49 (5) :935-41.|[2]Kojima K. Safety evaluation of disodium 5'-inosinate, disodium 5'-guanylate and disodium 5'-ribonucleotide. Toxicology. 1974 Jun;2 (2) :185-206.