Recombinant Human Her2/ERBB2 Protein

<strong>Recombinant Human Her2/ERBB2 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2019271_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 95.75 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> c-ERB-2 Protein, Human; c-ERB2 Protein, Human; CD340 Protein, Human; HER-2 Protein, Human; HER-2/neu Protein, Human; HER2 Protein, Human; MLN 19 Protein, Human; MLN-19 Protein, Human; MLN19 Protein, Human; NEU Protein, Human; NGL Protein, Human; p185(erbB2) Protein, Human; TKR1 Protein, Human; VSCN2 Protein, Human_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Wielgos ME, Rajbhandari R, Cooper TS, Wei S, Nozell S, Yang ES. Let-7 Status Is Crucial for PARP1 Expression in HER2-Overexpressing Breast Tumors Mol Cancer Res. 2017 Mar;15(3):340-347._x000D_ 2: Kanthala S, Mill CP, Riese DJ 2nd, Jaiswal M, Jois S. Expression and purification of HER2 extracellular domain proteins in Schneider2 insect cells Protein Expr Purif. 2016 Sep;125:26-33._x000D_ 3: Chopra A. (111)In-Labeled anti-epidermal growth factor receptor Affibody PEP09239 2013 Mar 28 [updated 2013 May 2]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013._x000D_ 4: Chopra A. (11)C/(68)Ga-Labeled sel-tagged anti-epidermal growth factor receptor 2 affibody Z(HER2:342) 2012 Oct 2 [updated 2012 Oct 25]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013._x000D_ 5: Kurokawa H, Arteaga CL. ErbB (HER) receptors can abrogate antiestrogen action in human breast cancer by multiple signaling mechanisms Clin Cancer Res. 2003 Jan;9(1 Pt 2):511S-5S._x000D_ 6: Albarakati N, Al-Ghamdi H, Al-Sowayan B, Alshareeda A. Homologous recombination mRNAs (RAD21, RAD50 and BARD1) have a potentially poor prognostic role in ERBB2-low bladder cancer patients Sci Rep. 2023 Jul 20;13(1):11738._x000D_ 7: Zhou H, Hittelman WN, Yagita H, Cheung LH, Martin SS, Winkles JA, Rosenblum MG. Antitumor activity of a humanized, bivalent immunotoxin targeting fn14-positive solid tumors Cancer Res. 2013 Jul 15;73(14):4439-50._x000D_ 8: Plowman GD, Green JM, Culouscou JM, Carlton GW, Rothwell VM, Buckley S. Heregulin induces tyrosine phosphorylation of HER4/p180erbB4 Nature. 1993 Dec 2;366(6454):473-5._x000D_ 9: Chopra A. (111)In/(68)Ga-Labeled anti-epidermal growth factor receptor, native chemical ligation cyclized Affibody Z(HER2:342min) 2013 Apr 3 [updated 2013 May 23]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/25055963">10: Eldridge S, Guo L, Mussio J, Furniss M, Hamre J 3rd, Davis M. Examining the protective role of ErbB2 modulation in human-induced pluripotent stem cell-derived cardiomyocytes Toxicol Sci. 2014 Oct;141(2):547-59. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant Human Her2/ERBB2 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>