S (-) -8-OH-DPAT (hydrobromide)

S (-) -8-OH-DPAT (S (-) -8-Hydroxy-2-dipropylaminotetralin) hydrobromide is an enantiomer of 8-OH-DPAT hydrobromide. 8-OH-DPAT hydrobromide is a potent, selective 5-HT1A agonist with a pIC50 of 8.19[1].

Product Specifications

CAS Number

[78095-20-2]

Product Name Alternative

S (-) -8-Hydroxy-2-dipropylaminotetralin (hydrobromide)

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/s-minus-8-oh-dpat-hydrobromide.html

Smiles

OC1=C2C[C@@H](N(CCC)CCC)CCC2=CC=C1.Br

Molecular Formula

C16H26BrNO

Molecular Weight

328.29

Precautions

P261-P280-P302+P352

References & Citations

[1]Wierońska JM, et al. The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-HT1A receptor signaling: mechanistic studies. Psychopharmacology (Berl) . 2015 Jan;232 (1) :259-73.