para-iodoHoechst 33258
Product Specifications
UNSPSC Description
para-iodoHoechst 33258 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1].
Target Antigen
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/para-iodoHoechst-33258.html
Solubility
DMSO : 20.5 mg/mL (ultrasonic;warming)
Smiles
CN1CCN(C2=CC=C3N=C(C4=CC=C5N=C(C6=CC=C(I)C=C6)NC5=C4)NC3=C2)CC1
Molecular Weight
534.39
References & Citations
[1]a b c "Hoechst Stains". Invitrogren (Molecular Probes).|[2]Portugal J, Waring MJ. Assignment of DNA binding sites for 4',6-diamidine-2-phenylindole and bisbenzimide (Hoechst 33258). A comparative footprinting study. Biochimica et Biophysica Acta 949 (2): 158-68.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-15632/para-iodoHoechst-33258-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-15632/para-iodoHoechst-33258-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
158013-43-5
Available Sizes
Curated Selection
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