Flavokawain C
Flavokawain C is a natural chalcone found in Kava root. Flavokawain C exerts cytotoxicity against human cancer cell lines, with an IC50 of 12.75 μM for HCT 116 cells[1].
Product Specifications
CAS Number
[37308-75-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/flavokawain-c.html
Purity
99.79
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1=C(OC)C=C(OC)C=C1O)/C=C/C2=CC=C(O)C=C2
Molecular Formula
C17H16O5
Molecular Weight
300.31
Precautions
H302, H315, H319, H335
References & Citations
[1]Phang CW, et al. Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells. PLoS One. 2016 Feb 9;11 (2) :e0148775.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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