CB-6673567
Product Specifications
UNSPSC Description
CB-6673567 is a selective AC1 inhibitor with an IC50 of 77 μM .CB-6673567blocks the choline-induced cAMP increase and can be used for cardiovascular diseases research[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/cb-6673567.html
Smiles
OC1=C2OCOC2=CC=C1C3=NNC=C3C4=CN(C5=CC=CC=C5)N=C4
Molecular Weight
346.34
References & Citations
[1]Brand CS, et al. Isoform selectivity of adenylyl cyclase inhibitors: characterization of known and novel compounds. J Pharmacol Exp Ther. 2013 Nov;347(2):265-75.|[2]Cheng Q, et al. Activation of α7 nicotinic acetylcholine receptors increases intracellular cAMP levels via activation of AC1 in hippocampal neurons. Neuropharmacology. 2015 Aug;95:405-14.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-101863/CB-6673567-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-101863/
Clinical Information
No Development Reported
CAS Number
379218-90-3
Curated Selection
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