CB-6673567
CB-6673567 is a selective AC1 inhibitor with an IC50 of 77 μM .CB-6673567blocks the choline-induced cAMP increase and can be used for cardiovascular diseases research[1].
Product Specifications
CAS Number
379218-90-3
UNSPSC
12352005
Target
Adenylate Cyclase
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/cb-6673567.html
Smiles
OC1=C2OCOC2=CC=C1C3=NNC=C3C4=CN(C5=CC=CC=C5)N=C4
Molecular Formula
C19H14N4O3
Molecular Weight
346.34
References & Citations
[1]Brand CS, et al. Isoform selectivity of adenylyl cyclase inhibitors: characterization of known and novel compounds. J Pharmacol Exp Ther. 2013 Nov;347 (2) :265-75.|[2]Cheng Q, et al. Activation of α7 nicotinic acetylcholine receptors increases intracellular cAMP levels via activation of AC1 in hippocampal neurons. Neuropharmacology. 2015 Aug;95:405-14.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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