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SA-15-P

SA-15-P inhibits LAG-3/MHCII and LAG-3/FGL1 interactions with IC50 values of 4.21 and 6.52 μM respectively. LAG-3/MHCII interaction is a target for immunotherapies[1].

Product Specifications

CAS Number

852846-00-5

UNSPSC

12352005

Target

LAG-3

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/sa-15-p.html

Smiles

O=C(C1=CC=CO1)NC2=CC=C(C=C2)OCC(C3=C(C)N(CC4=CC=CC=C4)C(C)=C3)=O

Molecular Formula

C26H24N2O4

Molecular Weight

428.48

References & Citations

[1]Abdel-Rahman SA, et al. Discovery of First-in-Class Small Molecule Inhibitors of Lymphocyte Activation Gene 3 (LAG-3) . ACS Med Chem Lett. 2023 Apr 11;14 (5) :629-635.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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