SA-15-P
SA-15-P inhibits LAG-3/MHCII and LAG-3/FGL1 interactions with IC50 values of 4.21 and 6.52 μM respectively. LAG-3/MHCII interaction is a target for immunotherapies[1].
Product Specifications
CAS Number
852846-00-5
UNSPSC
12352005
Target
LAG-3
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sa-15-p.html
Smiles
O=C(C1=CC=CO1)NC2=CC=C(C=C2)OCC(C3=C(C)N(CC4=CC=CC=C4)C(C)=C3)=O
Molecular Formula
C26H24N2O4
Molecular Weight
428.48
References & Citations
[1]Abdel-Rahman SA, et al. Discovery of First-in-Class Small Molecule Inhibitors of Lymphocyte Activation Gene 3 (LAG-3) . ACS Med Chem Lett. 2023 Apr 11;14 (5) :629-635.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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