Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Chenodeoxycholic Acid (Standard)

Chenodeoxycholic Acid (Standard) is the analytical standard of Chenodeoxycholic Acid. This product is intended for research and analytical applications. Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.

Product Specifications

CAS Number

[474-25-9]

Product Name Alternative

CDCA (Standard)

UNSPSC

12352211

Hazard Statement

H315-H319

Target

Autophagy; Endogenous Metabolite; FXR; Reference Standards

Type

Reference Standards

Related Pathways

Autophagy; Metabolic Enzyme/Protease; Others

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/chenodeoxycholic-acid-standard.html

Purity

99.80

Smiles

O=C(O)CC[C@@H](C)[C@]1([H])[C@]2(C)[C@](CC1)([H])[C@]3([H])[C@H](O)C[C@@](C4)([H])[C@@](CC[C@H]4O)(C)[C@]([H])3CC2

Molecular Formula

C24H40O4

Molecular Weight

392.57

Precautions

P264-P280-P302+P352-P362

References & Citations

[1]Stauffer AT, et al. Chenodeoxycholic acid and deoxycholic acid inhibit 11 beta-hydroxysteroid dehydrogenase type 2 and cause cortisol-induced transcriptional activation of the mineralocorticoid receptor. J Biol Chem. 2002 Jul 19;277 (29) :26286-92|[2]Casaburi I, et al. Chenodeoxycholic acid through a TGR5-dependent CREB signaling activation enhances cyclin D1 expression and promotes human endometrial cancer cell proliferation. Cell Cycle. 2012 Jul 15;11 (14) :2699-710|[3]Kawabe Y, et al. The molecular mechanism of the induction of the low density lipoprotein receptor by chenodeoxycholic acid in cultured human cells. Biochem Biophys Res Commun. 1995 Mar 8;208 (1) :405-11.|[4]Ao M, et al. Chenodeoxycholic acid stimulates Cl (-) secretion via cAMP signaling and increases cystic fibrosis transmembrane conductance regulator phosphorylation in T84 cells. Am J Physiol Cell Physiol. 2013 Aug 15;305 (4) :C447-56|[5]Noh K, et al. Farnesoid X receptor activation by chenodeoxycholic acid induces detoxifying enzymes through AMP-activated protein kinase and extracellular signal-regulated kinase 1/2-mediated phosphorylation of CCAAT/enhancer binding protein β. Drug Metab

Shipping Conditions

Blue Ice

Storage Conditions

4°C, sealed storage, away from light and moisture

Scientific Category

Reference Standards

Clinical Information

Launched

Isoform

Human Endogenous Metabolite

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

PUM1 Overexpression Lysate (Native) - (Dry Ice)
NBP2-10310 0.1 mg

PUM1 Overexpression Lysate (Native) - (Dry Ice)

Ask
View Details
Anti-Human MAPT/Tau/PHF-tau Antibody (MC1)
HY086203-01 50 µg

Anti-Human MAPT/Tau/PHF-tau Antibody (MC1)

Ask
View Details
Anti-Human MAPT/Tau/PHF-tau Antibody (MC1)
HY086203-02 100 µg

Anti-Human MAPT/Tau/PHF-tau Antibody (MC1)

Ask
View Details
Anti-Human MAPT/Tau/PHF-tau Antibody (MC1)
HY086203-03 1 mg

Anti-Human MAPT/Tau/PHF-tau Antibody (MC1)

Ask
View Details
CDI-Activated Separopore® 6B-CL
20181084-2 25 mL

CDI-Activated Separopore® 6B-CL

Ask
View Details
IL-1 Beta Polyclonal Antibody FITC Conjugated
MBS9462334-01 0.1 mL

IL-1 Beta Polyclonal Antibody FITC Conjugated

Ask
View Details