(S, R, R) -VH032
(S, R, R) -VH032 is a VHL ligand. (S, R, R) -VH032 can be used for synthesis of PROTAC NCOA4 degrader-1.
Product Specifications
CAS Number
2489876-59-5
UNSPSC
12352005
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/s-r-r-vh032.html
Smiles
CC1=C(SC=N1)C(C=C2)=CC=C2CNC([C@H]3N(C[C@@H](C3)O)C([C@H](N)C(C)(C)C)=O)=O
Molecular Formula
C22H30N4O3S
Molecular Weight
430.56
References & Citations
[1]Jian’ai Ji, et al. Discovery of a NCOA4 Degrader for Labile Iron-Dependent Ferroptosis Inhibition. Journal of Medicinal Chemistry 2024 67 (15), 12521-12533
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Von Hippel-Lindau (VHL)
Frequently Asked Questions
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