ERD-3111
ERD-3111 (Compound 44) is an orally active PROTAC ERα degrader (DC50: 0.5 nM) . ERD-3111 inhibits tumor growth in the parental MCF-7 xenograft model with wild-type ER and two clinically relevant ESR1 mutated mice model. ERD-3111 can be used in the research of ER+ breast cancer[1].
Product Specifications
CAS Number
2832865-25-3
UNSPSC
12352005
Target
Estrogen Receptor/ERR; PROTACs
Type
Reference compound
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/erd-3111.html
Purity
98.72
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC(CN1[C@@H](CC2=C([C@H]1C3=C(C=C(C=C3F)N4CCC5(CC4)CCN(C(CN6CC(C=C(C7=C8)C(N(C7=O)C9CCC(NC9=O)=O)=O)=C8C6)=O)CC5)F)C=CC%10=C2C=NN%10)C)F
Molecular Formula
C45H46F4N8O5
Molecular Weight
854.89
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![Cyclin T1 (CCNT1) Rabbit Monoclonal Antibody [Clone ID: R04-1G1]](https://cdn.genprice.uk/products/937/68dd1b60061270361ea12244/imageurl/ta421437.webp)
Cyclin T1 (CCNT1) Rabbit Monoclonal Antibody [Clone ID: R04-1G1]
PLAP (Placental Alkaline Phosphatase) (GM022), CF660R conjugate, 0.1mg/mL
