T7 Peptide

T7 peptide (Tumstatin (74-98), human) is an endothelial cell-specific inhibitor. T7 peptide interacts with αVβ3 integrin to inhibit the FAK, PI3-kinase, PKB/Akt, and mTOR signaling pathways in endothelial cells, ultimately suppressing protein synthesis and inducing apoptosis[1].

Product Specifications

Product Name Alternative

Tumstatin (74-98), human

UNSPSC

12352209

Target

Apoptosis; FAK; Integrin; mTOR

Type

Peptides

Related Pathways

Apoptosis; Cytoskeleton; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/t7-peptide.html

Solubility

10 mM in DMSO

Smiles

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