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Anti-Hu CD187 APC

CD187 (CXCR7) is a member of chemokine receptor family, but with discussed specificity. It is expressed in various tissues and cells, such as placenta, urinary bladder, fetal liver cells, tumor cells, activated endothelium, monocytes, lymphocytes, mature dendritic cells, and other.

Product Specifications

Certification

RUO

Reactivity

Human

Target Antigen

CD187

Clone

10D1-J16

Applications

FC (QC tested)

Format

APC

Buffer

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

References & Citations

*Doijen J, Van Loy T, De Haes W, Landuyt B, Luyten W, Schoofs L, Schols D: Signaling properties of the human chemokine receptors CXCR4 and CXCR7 by cellular electric impedance measurements. PLoS One. 2017 Sep 25;12 (9) :e0185354., URL: https://pubmed.ncbi.nlm.nih.gov/28945785/, *Espinoza-Sánchez NA, Vadillo E, Balandrán JC, Monroy-García A, Pelayo R, Fuentes-Pananá EM: Evidence of lateral transmission of aggressive features between different types of breast cancer cells. Int J Oncol. 2017 Nov;51 (5) :1482-1496., URL: https://pubmed.ncbi.nlm.nih.gov/29048610/, *Guan L, Li X, Wei J, Liang Z, Yang J, Weng X, Wu X: Antigen-specific CD8+ memory stem T cells generated from human peripheral blood effectively eradicate allogeneic targets in mice. Stem Cell Res Ther. 2018 Dec 7;9 (1) :337., URL: https://pubmed.ncbi.nlm.nih.gov/30526661/

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Specificity

The mouse monoclonal antibody 10D1-J16 recognizes an extracellular epitope on CD187/CXCR7, a transmembrane protein of chemokine receptor family.

Applications Notes

6

Isotype

Mouse IgG2a kappa

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