Bryonolic acid

Bryonolic acid is an active triterpenoid compound with immunomodulatory, anti-inflammatory, antioxidant and anticancer activities[1][2][3].

Product Specifications

CAS Number

[24480-45-3]

UNSPSC

12352211

Target

NO Synthase

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bryonolic-acid.html

Solubility

10 mM in DMSO

Smiles

C[C@@]12[C@]([C@@]3([H])[C@@](CC1)(CC[C@@](C)(C3)C(O)=O)C)(CCC4=C2CC[C@]5([H])[C@@]4(CC[C@@H](C5(C)C)O)C)C

Molecular Formula

C30H48O3

Molecular Weight

456.70

References & Citations

[1]Pornpatsorn Lertphadungkit, et al. Enhanced Production of Bryonolic Acid in Trichosanthes cucumerina L. (Thai Cultivar) Cell Cultures by Elicitors and Their Biological Activities. Plants (Basel) . 2020 Jun 2;9 (6) :709.|[2]Farid Khallouki, et al. Bryonolic Acid Blocks Cancer Cell Clonogenicity and Invasiveness through the Inhibition of Fatty Acid: Cholesteryl Ester Formation. Biomedicines. 2018 Feb 12;6 (1) :21.|[3]Tonibelle N Gatbonton-Schwager , et al. Bryonolic acid transcriptional control of anti-inflammatory and antioxidant genes in macrophages in vitro and in vivo. J Nat Prod. 2012 Apr 27;75 (4) :591-8.