Citrullinated Vimentin Human Recombinant

<strong>Citrullinated Vimentin Human Recombinant</strong>_x000D_ <strong>Catalog number:</strong> B2017411_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 53.5 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> N/A_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Brentville VA, Metheringham RL, Gunn B, Symonds P, Daniels I, Gijon M, Cook K, Xue W, Durrant LG. Citrullinated Vimentin Presented on MHC-II in Tumor Cells Is a Target for CD4+ T-Cell-Mediated Antitumor Immunity Cancer Res. 2016 Feb 1;76(3):548-60._x000D_ 2: Vossenaar ER, Després N, Lapointe E, van der Heijden A, Lora M, Senshu T, van Venrooij WJ, Ménard HA. Rheumatoid arthritis specific anti-Sa antibodies target citrullinated vimentin Arthritis Res Ther. 2004;6(2):R142-50._x000D_ 3: Pang SY, Liu HY, Huang YJ, Liu YF, Dai YM, Zeng P, Zeng HS. Diagnostic performance of anti-citrullinated protein/peptide antibodies in juvenile idiopathic arthritis Genet Mol Res. 2016 May 13;15(2)._x000D_ 4: Jenning M, Marklein B, Ytterberg J, Zubarev RA, Joshua V, van Schaardenburg D, van de Stadt L, Catrina AI, Nonhoff U, Häupl T, Konthur Z, Burmester GR, Skriner K. Bacterial citrullinated epitopes generated by Porphyromonas gingivalis infection-a missing link for ACPA production Ann Rheum Dis. 2020 Sep;79(9):1194-1202._x000D_ 5: Corsiero E, Bombardieri M, Carlotti E, Pratesi F, Robinson W, Migliorini P, Pitzalis C. Single cell cloning and recombinant monoclonal antibodies generation from RA synovial B cells reveal frequent targeting of citrullinated histones of NETs Ann Rheum Dis. 2016 Oct;75(10):1866-75._x000D_ 6: Grönwall C, Amara K, Hardt U, Krishnamurthy A, Steen J, Engström M, Sun M, Ytterberg AJ, Zubarev RA, Scheel-Toellner D, Greenberg JD, Klareskog L, Catrina AI, Malmström V, Silverman GJ. Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis J Autoimmun. 2017 Nov;84:29-45._x000D_ 7: Bang H, Egerer K, Gauliard A, Lüthke K, Rudolph PE, Fredenhagen G, Berg W, Feist E, Burmester GR. Mutation and citrullination modifies vimentin to a novel autoantigen for rheumatoid arthritis Arthritis Rheum. 2007 Aug;56(8):2503-11._x000D_ 8: Ishigami A, Masutomi H, Handa S, Nakamura M, Nakaya S, Uchida Y, Saito Y, Murayama S, Jang B, Jeon YC, Choi EK, Kim YS, Kasahara Y, Maruyama N, Toda T. Mass spectrometric identification of citrullination sites and immunohistochemical detection of citrullinated glial fibrillary acidic protein in Alzheimer's disease brains J Neurosci Res. 2015 Nov;93(11):1664-74._x000D_ 9: Corsiero E, Caliste M, Jagemann L, Fossati-Jimack L, Goldmann K, Cubuk C, Ghirardi GM, Prediletto E, Rivellese F, Alessandri C, Hopkinson M, Javaheri B, Pitsillides AA, Lewis MJ, Pitzalis C, Bombardieri M. Autoimmunity to stromal-derived autoantigens in rheumatoid ectopic germinal centers exacerbates arthritis and affects clinical response J Clin Invest. 2024 Apr 30;134(12):e169754._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/31048864">10: García-Moreno C, Gómara MJ, Bleda MJ, Sanmartí R, Haro I. Development of a multiplex assay based on chimeric citrullinated peptides as proof of concept for diagnosis of rheumatoid arthritis PLoS One. 2019 May 2;14(5):e0215927. </a>_x000D_ _x000D_ <strong>Products Related to Citrullinated Vimentin Human Recombinant can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>