KR-33493
KR-33493 is a potent inhibitor of Fas-mediated cell death (FAF1) .
Product Specifications
CAS Number
[1021497-97-1]
UNSPSC
12352005
Target
TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/KR-33494.html
Concentration
10mM
Purity
99.94
Solubility
DMSO : ≥ 31 mg/mL
Smiles
OC(C1=NN(CCC2=CC=CC=C2)C=C1NC(CSC3=CC=C(Br)C=C3)=O)=O
Molecular Formula
C20H18BrN3O3S
Molecular Weight
460.34
References & Citations
[1]Jeong JW, et al. Subacute toxicity evaluation of KR-33493, FAF1 inhibitor for a new anti-parkinson's disease agent, after oral administration in rats and dogs. Regul Toxicol Pharmacol. 2016 Nov;81:387-396.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TNFRSF6/Fas/CD95
Available Sizes
Curated Selection
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