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5-Iodo-cytidine

Product Specifications

UNSPSC Description

5-Iodo-cytidine (5-Iodo-D-cytidine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Target Antigen

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/5-iodo-cytidine.html

Purity

98.21

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(N=C(N)C(I)=C1)N1[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O

Molecular Weight

369.11

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-W008615/5-Iodo-cytidine-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W008615/5-Iodo-cytidine-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1147-23-5

Available Sizes

Curated Selection

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