HDAC-IN-74

HDAC-IN-74 (PA) is a dual HDAC/Rribonucleotide reductase (RR) inhibitor, with IC50 values of 10.80 μM and 9.34 μM for HDAC and HDAC, respectively. HDAC-IN-74 can be used in anticancer research[1].

Product Specifications

CAS Number

[1449310-17-1]

UNSPSC

12352005

Target

DNA/RNA Synthesis; HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hdac-in-74.html

Smiles

O=C(NO)CCCCCCC(NC1=C2C=CC=NC2=C3N=CC=CC3=C1)=O

Molecular Formula

C20H22N4O3

Molecular Weight

366.41

References & Citations

[1]Shetty MG, et al. Evaluation of 1,10-phenanthroline-based hydroxamate derivative as dual histone deacetylases/ribonucleotide reductase inhibitor with antitumor activities. Daru. 2024 Jun;32 (1) :263-278.