Fmoc-NH-PEG8-CH2CH2COOH
Fmoc-NH-PEG8-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[756526-02-0]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-nh-peg8-ch2ch2cooh.html
Purity
98.77
Solubility
10 mM in DMSO
Smiles
O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)O
Molecular Formula
C34H49NO12
Molecular Weight
663.75
Precautions
H302, H315, H319, H335
References & Citations
[1]Fulcher JM, et al. Chemical synthesis of Shiga toxin subunit B using a next-generation traceless "helping hand" solubilizing tag. Org Biomol Chem. 2019 Dec 28;17 (48) :10237-10244.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; PEG Linkers
Available Sizes
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