α-Casozepine
α-Casozepine is a bioactive peptide derived from the α protein S1 casein in milk and has an affinity for γ-aminobutyric acid (GABA) receptors in the brain. α-Casozepine has anti-anxiety effects[1][2].
Product Specifications
CAS Number
117592-45-7
UNSPSC
12352209
Target
GABA Receptor
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/α-casozepine.html
Purity
99.36
Solubility
DMSO : 20 mg/mL (ultrasonic; warming) |H2O : 66.67 mg/mL (ultrasonic; adjust pH to 2 with 1 M HCl)
Smiles
OC(C=C1)=CC=C1C[C@H](NC(CNC([C@H](CC(C)C)NC([C@@H](N)CC2=CC=C(C=C2)O)=O)=O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O
Molecular Formula
C60H94N14O16
Molecular Weight
1267.47
References & Citations
[1]Miclo L, et al. Characterization of alpha-casozepine, a tryptic peptide from bovine alpha (s1) -casein with benzodiazepine-like activity. FASEB J. 2001 Aug;15 (10) :1780-2.|[2]Landsberg G, et al Therapeutic effects of an alpha-casozepine and L-tryptophan supplemented diet on fear and anxiety in the cat. J Feline Med Surg. 2017 Jun;19 (6) :594-602.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
