Human Recombinant Pleckstrin Protein

<strong>Human Recombinant Pleckstrin Protein</strong>_x000D_ <strong>Catalog number:</strong> B2012627_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 41.9 kDa_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> Pleckstrin Protein, Human, Recombinant (His Tag)_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Yang XL, Zhang YL, Lai ZS, Xing FY, Liu YH. Pleckstrin homology domain of G protein-coupled receptor kinase-2 binds to PKC and affects the activity of PKC kinase World J Gastroenterol. 2003 Apr;9(4):800-3._x000D_ 2: Espejo A, Côté J, Bednarek A, Richard S, Bedford MT. A protein-domain microarray identifies novel protein-protein interactions Biochem J. 2002 Nov 1;367(Pt 3):697-702._x000D_ 3: Wang DS, Miller R, Shaw R, Shaw G. The pleckstrin homology domain of human beta I sigma II spectrin is targeted to the plasma membrane in vivo Biochem Biophys Res Commun. 1996 Aug 14;225(2):420-6._x000D_ 4: Rodriguez MM, Ron D, Touhara K, Chen CH, Mochly-Rosen D. RACK1, a protein kinase C anchoring protein, coordinates the binding of activated protein kinase C and select pleckstrin homology domains in vitro Biochemistry. 1999 Oct 19;38(42):13787-94._x000D_ 5: Touhara K, Inglese J, Pitcher JA, Shaw G, Lefkowitz RJ. Binding of G protein beta gamma-subunits to pleckstrin homology domains J Biol Chem. 1994 Apr 8;269(14):10217-20._x000D_ 6: Perisic L, Lal M, Hulkko J, Hultenby K, Önfelt B, Sun Y, Dunér F, Patrakka J, Betsholtz C, Uhlen M, Brismar H, Tryggvason K, Wernerson A, Pikkarainen T. Plekhh2, a novel podocyte protein downregulated in human focal segmental glomerulosclerosis, is involved in matrix adhesion and actin dynamics Kidney Int. 2012 Nov;82(10):1071-83._x000D_ 7: Lee SY, Mansour M, Pohajdak B. B2-1, a Sec7- and pleckstrin homology domain-containing protein, localizes to the Golgi complex Exp Cell Res. 2000 May 1;256(2):515-21._x000D_ 8: Li P, Xu Y, Li X, Bartlam M. Crystallization and preliminary X-ray crystallographic analysis of the human CKIP-1 pleckstrin homology domain Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Mar 1;69(Pt 3):324-7._x000D_ 9: Kimber WA, Trinkle-Mulcahy L, Cheung PC, Deak M, Marsden LJ, Kieloch A, Watt S, Javier RT, Gray A, Downes CP, Lucocq JM, Alessi DR. Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo Biochem J. 2002 Feb 1;361(Pt 3):525-36._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/15573383">10: Civera C, Simon B, Stier G, Sattler M, Macias MJ. Structure and dynamics of the human pleckstrin DEP domain: distinct molecular features of a novel DEP domain subfamily Proteins. 2005 Feb 1;58(2):354-66. </a>_x000D_ _x000D_ <strong>Products Related to Human Recombinant Pleckstrin Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>