PCSK9, Mouse (HEK293, His)
Product Specifications
UNSPSC Description
The PCSK9 protein regulates cholesterol levels by degrading LDLR, VLDLR, LRP1/APOER, and LRP8/APOER2 receptors. It promotes LDLR degradation, inhibits recycling, induces ubiquitination, and affects APOB degradation. Additionally, PCSK9 influences BACE1 intermediates, ENaC surface expression, and neuronal apoptosis by modulating LRP8/APOER2 levels and anti-apoptotic signaling pathways. PCSK9 Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived PCSK9 protein, expressed by HEK293 , with C-6*His labeled tag. PCSK9 Protein, Mouse (HEK293, His), has molecular weight of 19.37 & 55 kDa, respectively.
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/pcsk9-protein-mouse-660a-a-hek293-c-his.html
Purity
96.50
Smiles
QDEDGDYEEL MLALPSQEDG LADEAAHVAT ATFRRCSKEA WRLPGTYIVV LMEETQRLQI EQTAHRLQTR AARRGYVIKV LHIFYDLFPG FLVKMSSDLL GLALKLPHVE YIEEDSFVFA QSIPWNLERI IPAWHQTEED RSPDGSSQVE VYLLDTSIQG AHREIEGRVT ITDFNSVPEE DGTRFHRQAS KCDSHGTHLA GVVSGRDAGV AKGTSLHSLR VLNCQGKGTV SGTLIGLEFI RKSQLIQPSG PLVVLLPLAG GYSRILNAAC RHLARTGVVL VAAAGNFRDD ACLYSPASAP EVITVGATNA QDQPVTLGTL GTNFGRCVDL FAPGKDIIGA SSDCSTCFMS QSGTSQAAAH VAGIVARMLS REPTLTLAEL RQRLIHFSTK DVINMAWFPE DQQVLTPNLV ATLPPSTHET GGQLLCRTVW SAHSGPTRTA TATARCAPEE ELLSCSSFSR SGRRRGDWIE AIGGQQVCKA LNAFGGEGVY AVARCCLVPR ANCSIHNTPA ARAGLETHVH CHQKDHVLTG CSFHWEVEDL SVRRQPALRS RRQPGQCVGH QAASVYASCC HAPGLECKIK EHGISGPSEQ VTVACEAGWT LTGCNVLPGA SLTLGAYSVD NLCVARVHDT ARADRTSGEA TVAAAICCRS RPSAKASWVQ
Molecular Weight
19.37 & 55 kDa
Shipping Conditions
Blue Ice
Storage Conditions
Stored at -20°C for 2 years
Available Sizes
Curated Selection
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