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(2-Chlorophenyl) diphenylmethanol

(2-Chlorophenyl) diphenylmethanol (UCL 1880) is an analog of the metabolite 2-chlorophen-diphenyl-methanol (CBM) of 2-chlorophenyl, The IC50 for sI (AHP) inhibition is 1-2 μM. (2-chlorophenyl) diphenylmethanol is a weak Ca2+ channel blocker[1].

Product Specifications

CAS Number

[66774-02-5]

Product Name Alternative

O-Chlorotriphenylmethanol

UNSPSC

12352005

Hazard Statement

H302, H315, H318, H335, H413

Target

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/2-chlorophenyl-diphenylmethanol.html

Purity

99.82

Solubility

10 mM in DMSO

Smiles

OC(C1=CC=CC=C1Cl)(C2=CC=CC=C2)C3=CC=CC=C3

Molecular Formula

C19H15ClO

Molecular Weight

294.77

Precautions

H302, H315, H318, H335, H413

References & Citations

[1]Shah MM, et al. Clotrimazole analogues: effective blockers of the slow afterhyperpolarization in cultured rat hippocampal pyramidal neurones. Br J Pharmacol. 2001 Feb;132 (4) :889-98.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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