K-Ras G12C-IN-1
Product Specifications
UNSPSC Description
K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C extracted from patent WO 2014152588 A1.
IC50 value:
Target: K-ras G12C inhibitor
Target Antigen
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein;MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/K-Ras-G12C-IN-1.html
Purity
98.19
Solubility
DMSO : ≥ 40 mg/mL
Smiles
ClC(C=C(OC)C(NCC(N1CCN(C(C=C)=O)CC1)=O)=C2)=C2C3=CC=CC=C3Cl
Molecular Weight
448.34
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-18604/K-Ras-G12C-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-18604/K-Ras-G12C-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1629265-17-3
Available Sizes
Curated Selection
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