K-Ras G12C-IN-1

K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C extracted from patent WO 2014152588 A1. IC50 value: Target: K-ras G12C inhibitor

Product Specifications

CAS Number

[1629265-17-3]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/K-Ras-G12C-IN-1.html

Purity

98.19

Solubility

DMSO : ≥ 40 mg/mL

Smiles

ClC(C=C(OC)C(NCC(N1CCN(C(C=C)=O)CC1)=O)=C2)=C2C3=CC=CC=C3Cl

Molecular Formula

C22H23Cl2N3O3

Molecular Weight

448.34

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

More Discoveries

Explore Other Products

Browse additional items from our catalog

GTR15253040 1 Vial

Lentiviral mouse Kctd1 shRNA (UAS) - Lentiviral mouseKctd1 shRNA (UAS, GFP) (25)

View Details

NBP2-89649CL1 0.1 mL

Rabbit Monoclonal Uteroglobin/SCGB1A1 Antibody (030) [CoraFluor 1]

View Details

357112-01 48 Tests

Lppr1 (Lipid phosphate phosphatase-related protein type 1) BioAssayTM ELISA Kit (Rat) discontinued

View Details

357112-02 96 Tests

Lppr1 (Lipid phosphate phosphatase-related protein type 1) BioAssayTM ELISA Kit (Rat) discontinued

View Details

MBS1031306-01 0.02 mg (E-Coli)

Recombinant Phomopsis amygdali Geranylgeranyl pyrophosphate synthase D (GGS-D)

View Details

MBS1031306-02 0.02 mg (Yeast)

Recombinant Phomopsis amygdali Geranylgeranyl pyrophosphate synthase D (GGS-D)

View Details