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COX-2-IN-42

COX-2-IN-42 (Compound T1) is a COX-2 inhibitor, and protects zebrafish against PTZ-induced neuronal damage[1].

Product Specifications

UNSPSC

12352005

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cox-2-in-42.html

Solubility

10 mM in DMSO

Smiles

O=S(C1=CC=C(N2N=C(C(N/N=C/C3=CC=CC(OC4=CC=CC=C4)=C3)=O)C=C2C5=CC=C(OC)C=C5)C=C1)(N)=O

Molecular Formula

C30H25N5O5S

Molecular Weight

567.62

References & Citations

[1]Murugan R, et al. Neuroprotective potential of pyrazole benzenesulfonamide derivative T1 in targeted intervention against PTZ-induced epilepsy-like condition in in vivo zebrafish model. Int Immunopharmacol. 2024 Mar 15;131:111859.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

COX-2

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