H15-LOX-2 inhibitor 3
H15-LOX-2 inhibitor 3 (Compound 13) is an inhibitor of h15-LOX, with IC50 and Ki values of 25 μM and 15.1 μM, respectively[1].
Product Specifications
CAS Number
[1164515-84-7]
UNSPSC
12352005
Target
Lipoxygenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/h15-lox-2-inhibitor-3.html
Smiles
O=C(C1=NN[C@H](C(N2C3=CC=C(C#N)C=C3)=O)[C@@H]1C2=O)C4=CC=C(C=CC=C5)C5=N4
Molecular Formula
C22H13N5O3
Molecular Weight
395.37
References & Citations
[1]Viviani L G, et al. Identification of novel human 15-lipoxygenase-2 (h15-LOX-2) inhibitors using a virtual screening approach[J]. bioRxiv, 2024: 2024.07. 21.604444.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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