H15-LOX-2 inhibitor 3

H15-LOX-2 inhibitor 3 (Compound 13) is an inhibitor of h15-LOX, with IC50 and Ki values of 25 μM and 15.1 μM, respectively[1].

Product Specifications

CAS Number

[1164515-84-7]

UNSPSC

12352005

Target

Lipoxygenase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/h15-lox-2-inhibitor-3.html

Smiles

O=C(C1=NN[C@H](C(N2C3=CC=C(C#N)C=C3)=O)[C@@H]1C2=O)C4=CC=C(C=CC=C5)C5=N4

Molecular Formula

C22H13N5O3

Molecular Weight

395.37

References & Citations

[1]Viviani L G, et al. Identification of novel human 15-lipoxygenase-2 (h15-LOX-2) inhibitors using a virtual screening approach[J]. bioRxiv, 2024: 2024.07. 21.604444.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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