TACA
TACA (trans-4-Aminocrotonic acid) is a potent agonist of GABAA and GABAC receptors (KD= 0.6 μM) . TACA also is GABA uptake inhibitor and substrate for GABA-T. TACA produces late biphasic responses in the MPG neurons[1][2][3].
Product Specifications
CAS Number
38090-53-8
Product Name Alternative
Trans-4-Aminocrotonic acid
UNSPSC
12352211
Hazard Statement
H301-H311-H331-H341
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/taca.html
Concentration
10mM
Purity
99.33
Solubility
DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 20 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)/C=C/CN
Molecular Formula
C4H7NO2
Molecular Weight
101.10
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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