22(R)-Hydroxycholesterol
Product Specifications
Product Name Alternative
Y-39983 (free base)
UNSPSC Description
22(R)-Hydroxycholesterol (Narthesterol) is an endogenous LXR agonist. 22(R)-Hydroxycholesterol (Narthesterol) can be used for tangier disease research[1].
Target Antigen
LXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/22-r-hydroxycholesterol.html
Purity
98.15
Solubility
Ethanol : ≥ 100 mg/mL
Smiles
O[C@@H](CC[C@@]12C)CC1=CC[C@@]3([C@@]2(CC[C@]4([C@]3(CC[C@]4([H])[C@H](C)[C@@H](CCC(C)C)O)[H])C)[H])[H]
Molecular Weight
402.65
References & Citations
[1]Costet P, et al. Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor. J Biol Chem. 2000 Sep 8;275(36):28240-5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116969/22-R-Hydroxycholesterol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116969/22-R-Hydroxycholesterol-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
17954-98-2
Available Sizes
Curated Selection
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