22 (R) -Hydroxycholesterol
22 (R) -Hydroxycholesterol (Narthesterol) is an endogenous LXR agonist. 22 (R) -Hydroxycholesterol (Narthesterol) can be used for tangier disease research[1].
Product Specifications
CAS Number
[17954-98-2]
Product Name Alternative
Narthesterol
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
LXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/22-r-hydroxycholesterol.html
Purity
99.86
Solubility
Ethanol : ≥ 100 mg/mL
Smiles
O[C@@H](CC[C@@]12C)CC1=CC[C@@]3([C@@]2(CC[C@]4([C@]3(CC[C@]4([H])[C@H](C)[C@@H](CCC(C)C)O)[H])C)[H])[H]
Molecular Formula
C27H46O2
Molecular Weight
402.65
Precautions
H302, H315, H319, H335
References & Citations
[1]Costet P, et al. Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor. J Biol Chem. 2000 Sep 8;275 (36) :28240-5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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