SIRT1 activator 1
SIRT1 activator 1 (compound 3) is a derivative of marine compound xyloallenoide A isolated from the mangrove fungus Xylaria sp.SIRT1 activator 1 shows angiogenic activities in zebrafish. SIRT1 activator 1 protects hEPC against AngII-induced senescence by increasing SIRT1 expression levels and balancing the AMPK/Akt signaling pathway[1].
Product Specifications
UNSPSC
12352211
Target
Sirtuin
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sirt1-activator-1.html
Solubility
10 mM in DMSO
Smiles
C[C@@H](NC([C@@H](NC([C@H](N)C(C)C)=O)CCCCNC(OC(C)(C)C)=O)=O)C(O)=O
Molecular Formula
C19H36N4O6
Molecular Weight
416.51
References & Citations
[1]Jing Yang, et al. Marine Compound Exerts Antiaging Effect in Human Endothelial Progenitor Cells via Increasing Sirtuin1 Expression. ACS Pharmacol. Transl. Sci. Publication Date:October 10, 2023
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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