SIRT1 activator 1
SIRT1 activator 1 (compound 3) is a derivative of marine compound xyloallenoide A isolated from the mangrove fungus Xylaria sp.SIRT1 activator 1 shows angiogenic activities in zebrafish. SIRT1 activator 1 protects hEPC against AngII-induced senescence by increasing SIRT1 expression levels and balancing the AMPK/Akt signaling pathway[1].
Product Specifications
UNSPSC
12352211
Target
Sirtuin
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sirt1-activator-1.html
Solubility
10 mM in DMSO
Smiles
C[C@@H](NC([C@@H](NC([C@H](N)C(C)C)=O)CCCCNC(OC(C)(C)C)=O)=O)C(O)=O
Molecular Formula
C19H36N4O6
Molecular Weight
416.51
References & Citations
[1]Jing Yang, et al. Marine Compound Exerts Antiaging Effect in Human Endothelial Progenitor Cells via Increasing Sirtuin1 Expression. ACS Pharmacol. Transl. Sci. Publication Date:October 10, 2023
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
