LIMK-IN-2

LIMK-IN-2 (Compound 52) is an LIMK inhibitor. LIMK-IN-2 can suppress the cell migration of osteosarcoma and cervical cancer cells, demonstrating potential anti-angiogenic activity[1].

Product Specifications

CAS Number

[2747216-27-7]

UNSPSC

12352005

Target

LIM Kinase (LIMK)

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/limk-in-2.html

Solubility

10 mM in DMSO

Smiles

COC1=CC=CC(C2=CC(NC(N3CCC(C4=C5C(NC=C5C6CC6)=NC=N4)=CC3)=O)=CC=C2)=C1

Molecular Formula

C28H27N5O2

Molecular Weight

465.55

References & Citations

[1]Champiré A, et al. Tetrahydropyridine LIMK inhibitors: Structure activity studies and biological characterization. Eur J Med Chem. Published online April 9, 2024.