LIMK-IN-2
LIMK-IN-2 (Compound 52) is an LIMK inhibitor. LIMK-IN-2 can suppress the cell migration of osteosarcoma and cervical cancer cells, demonstrating potential anti-angiogenic activity[1].
Product Specifications
CAS Number
[2747216-27-7]
UNSPSC
12352005
Target
LIM Kinase (LIMK)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/limk-in-2.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=CC(C2=CC(NC(N3CCC(C4=C5C(NC=C5C6CC6)=NC=N4)=CC3)=O)=CC=C2)=C1
Molecular Formula
C28H27N5O2
Molecular Weight
465.55
References & Citations
[1]Champiré A, et al. Tetrahydropyridine LIMK inhibitors: Structure activity studies and biological characterization. Eur J Med Chem. Published online April 9, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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