Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

AZD9898

AZD9898 is an orally active leukotriene-C4 synthetase (LTC4S, glutathione S-transferase II) inhibitor, with an IC50 of 0.28 nM. AZD9898 mitigates the GABA binding and hepatic toxicity signal. AZD9898 has the potential to treat asthma[1].

Product Specifications

UNSPSC

12352005

Target

Glutathione S-transferase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/azd9898.html

Purity

98.01

Solubility

DMSO : ≥ 250 mg/mL

Smiles

O=C([C@@H]1[C@@H](C(C2=NC=C(N(C3=CC(Cl)=C(F)C=C3F)CC(C)(F)C)N=C2OC)=O)C1)O

Molecular Formula

C20H19ClF3N3O4

Molecular Weight

457.83

References & Citations

[1]Munck Af Rosenschöld M, et al. Discovery of the Oral Leukotriene C4 Synthase Inhibitor (1S,2S) -2- ({5-[ (5-Chloro-2,4-difluorophenyl) (2-fluoro-2-methylpropyl) amino]-3-methoxypyrazin-2-yl}carbonyl) cyclopropanecarboxylic Acid (AZD9898) as a New Treatment for Asthma. J Med Chem. 2019 Aug 30.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-126329/AZD9898-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-126329/AZD9898-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

Phase 1

CAS Number

[2042347-69-1]

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Brain Protein I3 (BRI3) Mouse ELISA Kit
B9265 96 Tests

Brain Protein I3 (BRI3) Mouse ELISA Kit

Ask
View Details
Recombinant Deinococcus geothermalis Nucleoside diphosphate kinase (ndk)
MBS1342976-01 0.02 mg (E-Coli)

Recombinant Deinococcus geothermalis Nucleoside diphosphate kinase (ndk)

Ask
View Details
Recombinant Deinococcus geothermalis Nucleoside diphosphate kinase (ndk)
MBS1342976-02 0.1 mg (E-Coli)

Recombinant Deinococcus geothermalis Nucleoside diphosphate kinase (ndk)

Ask
View Details
Recombinant Deinococcus geothermalis Nucleoside diphosphate kinase (ndk)
MBS1342976-03 0.02 mg (Yeast)

Recombinant Deinococcus geothermalis Nucleoside diphosphate kinase (ndk)

Ask
View Details
Recombinant Deinococcus geothermalis Nucleoside diphosphate kinase (ndk)
MBS1342976-04 0.1 mg (Yeast)

Recombinant Deinococcus geothermalis Nucleoside diphosphate kinase (ndk)

Ask
View Details
Recombinant Deinococcus geothermalis Nucleoside diphosphate kinase (ndk)
MBS1342976-05 0.02 mg (Baculovirus)

Recombinant Deinococcus geothermalis Nucleoside diphosphate kinase (ndk)

Ask
View Details