1- (4-Chlorobenzhydryl) piperazine

1- (4-Chlorobenzhydryl) piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Product Specifications

CAS Number

[303-26-4]

UNSPSC

12352200

Hazard Statement

H315, H317, H318, H361

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/1-4-chlorobenzhydryl-piperazine.html

Purity

99.95

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

ClC1=CC=C(C(N2CCNCC2)C3=CC=CC=C3)C=C1

Molecular Formula

C17H19ClN2

Molecular Weight

286.81

Precautions

H315, H317, H318, H361

References & Citations

[1]Gaertner, HJ, Breyer, U., and Liomin, G.Chronic administration of chlorcyclizine and meclizine to rats: Accumulation of a metabolite formed by piperazine ring cleavage J. Pharmacol. Exp. Ther.185(2)195-201(1973)|[2]Kuntzman, R., Klutch, A., Tsai, I., et al.Physiological distribution and metabolic inactivation of chlorcyclizine and cyclizineJ. Pharmacol. Exp. Ther.149(1)29-35(1965)|[3]Simpson, D., Skellern, GG, and Miller, JHMethod for the control of known impurities in hydroxyzine hydrochlorideJ. Pharm . Biomed. Anal.14(8-10)1371-1375(1996)|[4]Javid, FS, Shafaat, A., and Zarghi, A. Determination of cetirizine and its impurities in bulk and tablet formulation using a validated capillary zone electrophoretic methodJ. Anal. Chem.69(5)442-447(2014)|[5]Back, SK, Kam, YL, Oh, JA, et al.Synthesis and evaluation of (4-chlorobenzhydryl) piperazine amides as sodium channel Nav7 inhibitorsBull. Korean Chem. Soc.36(9)2290-2297(2015)|[6]Yarim, M., Koksal, M., Durmaz, I., et al.Cancer cell cytotoxicities of 1-(4-substitutedbenzoyl)-4 -(4-chlorobenzhydryl)piperazine derivativesInt. J. Mol. Sci.13(7)8071-8085(2012)|[7]Narsaiah, AV, and Narssimha, P.Efficient synthesis of antihistamines clocinizine and chlorcyclizineMed. Chem. Res.21538- 541 (2012)