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Bazedoxifene (acetate) -D

Bazedoxifene (acetate) -D (TSE-424 (acetate) -D) is the D-crystal form compound of Bazedoxifene acetate (HY-A0036) . Bazedoxifene acetate is an orally active, nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively[1].

Product Specifications

CAS Number

[198481-33-3]

Product Name Alternative

TSE-424 (acetate) -D

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Estrogen Receptor/ERR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bazedoxifene-acetate-d.html

Purity

99.93

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

CC1=C(C2=CC=C(O)C=C2)N(CC3=CC=C(OCCN4CCCCCC4)C=C3)C5=CC=C(O)C=C51.CC(O)=O

Molecular Formula

C32H38N2O5

Molecular Weight

530.65

Precautions

H302, H315, H319, H335

References & Citations

[1]Barry S Komm, et al. Bazedoxifene acetate: a selective estrogen receptor modulator with improved selectivity. Endocrinology. 2005 Sep;146 (9) :3999-4008.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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