FHT-1204
FHT-1204 is a potent SMARCA4/SMARCA2 ATPase (BRG1 and BRM) inhibitor with IC50s of ≤10 nM (WO2020160180A1; compound 70) [1].
Product Specifications
CAS Number
[2468048-24-8]
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fht-1204.html
Purity
99.81
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CN(C=C1)S(C)(=O)=O)N[C@@H](COC)C(NC2=NC(C3=CC(C4=CC=NC=C4)=CC=C3)=CS2)=O
Molecular Formula
C24H23N5O5S2
Molecular Weight
525.60
References & Citations
[1]Rishi G. Vaswani, et al. Compounds and uses thereof. WO2020160180A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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