Calcium Green-5N AM

Calcium Green-5N AM is a novel Ca2+-sensitive fluorescent probe. Calcium Green-5N AM shows enhancement in fluorescence intensity on binding Ca2+, and can monitor free Ca2+ in neurons[1][2][3].

Product Specifications

CAS Number

[216699-33-1]

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/calcium-green-5n-am.html

Solubility

DMSO : 6.68 mg/mL (ultrasonic; warming)

Smiles

O=C1OC2(C3=CC(Cl)=C(C=C3OC4=CC(OC(C)=O)=C(C=C42)Cl)OC(C)=O)C5=CC=C(C(NC6=CC=C(N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C(OCCOC7=CC([N-]([O-])=O)=CC=C7N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)=C6)=O)C=C15

Molecular Formula

C59H52Cl2N4O28 2-

Molecular Weight

1335.96

References & Citations

[1]D Thomas, et al. A comparison of fluorescent Ca2+ indicator properties and their use in measuring elementary and global Ca2+ signals. Cell Calcium. 2000 Oct;28 (4) :213-23.|[2]S Rajdev, et al. Calcium green-5N, a novel fluorescent probe for monitoring high intracellular free Ca2+ concentrations associated with glutamate excitotoxicity in cultured rat brain neurons. Neurosci Lett. 1993 Nov 12;162 (1-2) :149-52.|[3]Scott B Herrick, et al. The acrosomal vesicle of mouse sperm is a calcium store. J Cell Physiol. 2005 Mar;202 (3) :663-71.