Taraxerol acetate
Taraxerol acetate is a COX-1 and COX-2 inhibitor with IC50 values of 116.3 μM and 94.7 μM, respectively. Taraxerol acetate the has the anticancer potential and induces cell apoptosis[1].
Product Specifications
CAS Number
2189-80-2
UNSPSC
12352211
Target
Apoptosis; COX
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/taraxerol-acetate.html
Solubility
10 mM in DMSO
Smiles
C[C@]12C3=CC[C@@](C)(CCC(C)(C)C4)[C@]4([H])[C@@]3(CC[C@]1([H])[C@@]5([C@@](C(C)([C@@H](OC(C)=O)CC5)C)([H])CC2)C)C
Molecular Formula
C32H52O2
Molecular Weight
468.75
References & Citations
[1]Ubaid Ur Rehman1 A, et al. Molecular docking of taraxerol acetate as a new COX inhibitor. Journal of the Bangladesh Pharmacological Society|[2]Hong JF, et al. Anticancer activity of taraxerol acetate in human glioblastoma cells and a mouse xenograft model via induction of autophagy and apoptotic cell death, cell cycle arrest and inhibition of cell migration.Mol Med Rep. 2016 Jun;13 (6) :4541-8.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
COX-1; COX-2
Available Sizes
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