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Metyrosine

Metyrosine is a selective tyrosine hydroxylase enzyme inhibitor. Metyrosine exerts anti-inflammatory and anti-ulcerative effects. Metyrosine significantly inhibits high COX-2 activity[1]. Metyrosine is a very effective agent for blood pressure control[2].

Product Specifications

CAS Number

[672-87-7]

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/metyrosine.html

Purity

99.64

Solubility

H2O : 5 mg/mL (ultrasonic; warming; adjust pH to 2 with HCl; heat to 60°C)

Smiles

C[C@](C(O)=O)(N)CC1=CC=C(O)C=C1

Molecular Formula

C10H13NO3

Molecular Weight

195.22

Precautions

H302, H312, H332

References & Citations

[1]Albayrak A, Polat B, Cadirci E, et al. Gastric anti-ulcerative and anti-inflammatory activity of metyrosine in rats. Pharmacol Rep. 2010;62 (1) :113‐119.|[2]Garg MK, et al. Medical management of pheochromocytoma: Role of the endocrinologist. Indian J Endocrinol Metab. 2011;15 Suppl 4 (Suppl4) :S329‐S336.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Available Sizes

Curated Selection

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